CNAnorm: A package to detect Copy Number Alterations (CNA) from sequencing data
نویسنده
چکیده
CNAnorm is a package for the analysis of Copy Number Alteration (CNA) of tumour samples using low coverage (around 0.01 0.5X) high throughput sequencing[1]. In particular, CNAnorm aims to perform a meaningful normalisation of the sample by estimation of the underlying tumour’s ploidy. CNAnorm allows both a fully automated as well as an interactive approach to the normalisation step. It provides serveral normalisation methods. If the user has some external information about the ploidy of the genome, it is possible to manually inform CNAnorm and then perform the normalisation. CNAnorm also provides a method for plotting the normalised genome profile. For more information and the original data, see the authors’ website.
منابع مشابه
CNAnorm: A package for normalization of CNA sequencing data
CNAnorm is a package for the analysis of Copy Number Alteration (CNA) of tumor samples using low coverage (around 0.01 0.5X) high throughput sequencing[1]. In particular, CNAnorm aims to perform a meaningful normalization of the sample by estimation of the underlying tumor’s ploidy. CNAnorm allows both a fully automated as well as an interactive approach to the normalization step. If the user h...
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